Product Information
17912-1-PBS targets KCNH5 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag12312 Product name: Recombinant human KCNH5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 640-988 aa of BC073979 Sequence: IIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDVKKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSTQGDPERNQLQVESRSLQNGTSITGTSVVTVSQITPIQTSLAYVKTSESLKQNNRDAMELKPNGGADQKCLKVNSPIRMKNGNGKGWLRLKNNMGAHEEKKEDWNNVTKAESMGLLSEDPKSSDSENSVTKNPLRKTDSCDSGITKSDLRLDKAGEARSPLEHSPIQADAKHPFYPIPEQALQTTLQEVKHELKEDIQLLSCRMTALEKQVAEILKILSEKSVPQASSPKSQMPLQVPPQIPCQDIFSVSRPESPESDKDEIHF Predict reactive species |
| Full Name | potassium voltage-gated channel, subfamily H (eag-related), member 5 |
| Calculated Molecular Weight | 988 aa, 112 kDa |
| Observed Molecular Weight | 69-71 kDa |
| GenBank Accession Number | BC073979 |
| Gene Symbol | KCNH5 |
| Gene ID (NCBI) | 27133 |
| RRID | AB_3085546 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NCM2 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Potassium voltage-gated channel subfamily H member 5 (KCNH5), also known as Ether-a-go-go potassium channel 2 (hEAG2) belongs to mammalian potassium channel subfamily and is upregulated in a subset of Medulloblastoma (MB). KCNH5 protein is confined intracellularly during interphase but is enriched in the plasma membrane during late G2 phase and mitosis (PMID: 22855790, 26258683).
