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KIAA0319L Polyclonal antibody, PBS Only

KIAA0319L Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 21016-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

AAVR, Adeno-associated virus receptor, Dyslexia-associated protein KIAA0319-like protein, KIAA0319 like, KIAA1837

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

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Freight/Packing: -

Quantity

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Product Information

21016-1-PBS targets KIAA0319L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag15263

Product name: Recombinant human KIAA0319L protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 233-582 aa of BC031672

Sequence: ATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSSDDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVNVIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEVLNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDINVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKGHEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENFIKVQLRDGDSNCEWSVLY

Predict reactive species
Full Name KIAA0319-like
Calculated Molecular Weight 1049 aa, 116 kDa
Observed Molecular Weight ~150 kDa
GenBank Accession NumberBC031672
Gene Symbol KIAA0319L
Gene ID (NCBI) 79932
RRIDAB_10733523
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8IZA0
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

KIAA0319L (also known as AAVR) is a type-I transmembrane protein that acts as a receptor for adeno-associated virus (AAV) and is involved in adeno-associated virus infection through endocytosis system (PMID: 26814968). It has been shown that KIAA0319L is highly-glycosylated and can localise to the plasma membrane, endosomes, Golgi and trans-Golgi network (TGN) (PMID: 29991750). KIAA0319L gene has been associated with susceptibility to developmental dyslexia or reading disabilities (PMID: 19085271). The predicted molecular mass of KIAA0319L is 116 kDa, but western blot detected protein at 150 kDa in lysate from HeLa cells, likely due to glycosidic linkages (PMID: 28679762; 30962536).

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