Product Information
84966-2-PBS targets Eg5 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Eg5 fusion protein Ag20001 Predict reactive species |
Full Name | kinesin family member 11 |
Calculated Molecular Weight | 1056 aa, 119 kDa |
Observed Molecular Weight | 120-130 kDa |
GenBank Accession Number | BC136474 |
Gene Symbol | Eg5 |
Gene ID (NCBI) | 3832 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P52732 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Eg5 is a plus-end-directed microtubule motor encoded by KIF11 gene. It is an essential mitotic kinesin that plays a pivotal role in the formation and maintenance of bipolar spindle during early prometaphase. Eg5 has been implicated in tumourigenesis, and its overexpression has been found in various cancer tissues.