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Anti-Human LAMP3 Rabbit Recombinant Antibody, PBS Only (98408-3-PBS)

Anti-Human LAMP3 Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human LAMP3 Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98408-3-PBS-1MG

LAMP3 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98408-3-PBS

Clone No.242748F3

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

CD208, DC LAMP, DCLAMP, DC-lysosome-associated membrane glycoprotein, LAMP

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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Filter: AllFC

FC experiment of human monocyte-derived dendritic using 98408-3-RR (same clone as 98408-3-PBS)
1x10^6 unstimulated human CD14+ monocytes or human monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human LAMP3 Rabbit RecAb (98408-3-RR, Clone: 242748F3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98408-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
FC experiment of human monocyte-derived dendritic using 98408-3-RR (same clone as 98408-3-PBS)
1x10^6 human monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human LAMP3/CD208 Rabbit RecAb (98408-3-RR, Clone: 242748F3) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 unstimulated human CD14+ monocytes were surface stained with 0.25 ug Anti-Human LAMP3/CD208 Rabbit RecAb (98408-3-RR, Clone: 242748F3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98408-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human monocyte-derived dendritic cells were surface stained with 0.25 ug Anti-Human LAMP3/CD208 Rabbit RecAb (98408-3-RR, Clone: 242748F3) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 unstimulated human CD14+ monocytes were surface stained with 0.25 ug Anti-Human LAMP3/CD208 Rabbit RecAb (98408-3-RR, Clone: 242748F3) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98408-3-PBS in a different storage buffer formulation.

Overview

Tested Applications
Product Information

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Product Information

98408-3-PBS targets LAMP3 in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg3594 Product name: Recombinant Human LAMP3 protein (rFc Tag) (HPLC verified) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 28-381 aa of NM_014398.4 Sequence: KAFPETRDYSQPTAAATVQDIKKPVQQPAKQAPHQTLAARFMDGHITFQTAATVKIPTTTPATTKNTATTSPITYTLVTTQATPNNSHTAPPVTEVTVGPSLAPYSLPPTITPPAHTTGTSSSTVSHTTGNTTQPSNQTTLPATLSIALHKSTTGQKPVQPTHAPGTTAAAHNTTRTAAPASTVPGPTLAPQPSSVKTGIYQVLNGSRLCIKAEMGIQLIVQDKESVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQGGFVNLTFTKDEESYYISEVGAYLTVSDPETIYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHFGNVDECSSDYT Predict reactive species
Full Name	lysosomal-associated membrane protein 3
Calculated Molecular Weight	44 kDa
GenBank Accession Number	NM_014398.4
Gene Symbol	LAMP3
Gene ID (NCBI)	27074
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	Q9UQV4
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

LAMP3 (lysosome-associated membrane protein 3), also known as DC-LAMP (DC-lysosome-associated membrane glycoprotein), TSC403, or CD208, is a highly glycosylated lysosomal membrane protein that belongs to the LAMP family. LAMP3 is expressed in lung type II pneumocytes, lymphoid organs, and dendritic cells. It might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells (PMID:9721848).