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LARP7 Polyclonal antibody, PBS Only

LARP7 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 17067-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

HDCMA18P, hLARP7, La related protein 7, La-related protein 7, PIP7S

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

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Freight/Packing: -

Quantity

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Product Information

17067-1-PBS targets LARP7 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag10891

Product name: Recombinant human LARP7 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 83-331 aa of BC006981

Sequence: LTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKDIIKEASEASKE

Predict reactive species
Full Name La ribonucleoprotein domain family, member 7
Calculated Molecular Weight 582 aa, 67 kDa
Observed Molecular Weight 67 kDa
GenBank Accession NumberBC006981
Gene Symbol LARP7
Gene ID (NCBI) 51574
RRIDAB_2132693
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ4G0J3
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

LARP7 belongs to the LARP RNA-binding protein family, which includes the lupus LA antigen gene, and modulates the metabolism and function of a variety of RNA species [PMID:20138158]. LARP7 binds to the 7SK RNP complex, and sequesters the positive transcription elongation factor b (P-TEFb) in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. binds to and stabilizes 7sk snRNA[PMID:19416841].

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