Anti-Mouse Ly-6G (1A8)

Ly-6G Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2a, kappa

Reactivity

Mouse and More (1)

Applications

IHC, IF, FC

Conjugate

Unconjugated

CloneNo.

1A8

Cat no : 65078-1-Ig

Synonyms

Gr1, Gr-1, Ly 6G, Ly6g, Ly-6G



Tested Applications

Positive FC detected inmouse bone marrow cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65078-1-Ig targets Ly-6G in IHC, IF, FC applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Cited Reactivitymouse
Host / Isotype Rat / IgG2a, kappa
Class Monoclonal
Type Antibody
Immunogen Ly-6G transfected EL-4J cell line
Full Name lymphocyte antigen 6 complex, locus G
GenBank Accession NumberX70920
Gene Symbol Ly-6G/Ly-6C
Gene ID (NCBI) 546644
RRIDAB_2918382
Conjugate Unconjugated
Form Liquid
Purification MethodAffinity purification
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

Background Information

Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The 1A8 mAb is specific for Ly-6G (PMID: 8360469).

Protocols

Product Specific Protocols
FC protocol for Ly-6G antibody 65078-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF

Eur J Pharmacol

Adelmidrol ameliorates liver ischemia-reperfusion injury through activating Nrf2 signaling pathway

Authors - Min Wu
mouseIHC

Inflamm Res

Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration

Authors - Hou-Ping Wang
mouseIF

Biochim Biophys Acta Mol Basis Dis

JuA alleviates liver ischemia-reperfusion injury by activating AKT/NRF2/HO-1 pathways

Authors - Haoran Fang