MAGEA1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55105-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
A375 cells, MCF-7 cells

Positive IF detected in:
A375 cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)

Calculated molecular weight:
34 kDa

Observed molecular weight:
46 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAGEA1

Synonyms
Antigen MZ2 E, Cancer/testis antigen 1.1, CT1.1, MAGE 1 antigen, MAGE1, MAGE1A, MAGEA1, Melanoma associated antigen 1
Background

MAGEA1, also named as CT1.1, MZ2-E, MAGE1 and MAGE1A, is the first gene reported to encode a CTL-defined human tumor antigen. It may play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. MAGEA1 provided direct evidence for the power of the cDNA expression library as an effective strategy to identify genes encoding tumor antigens recognized by HLA-restricted T cells.(PMID:16951217 ) The antibody is specific to MAGEA1.


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