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LC3C-Specific Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 18726-1-AP

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Con: 35 μg/150 μl

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Tested Applications

Applications:
WB, IF, ELISA
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Images See all

LC3C-Specific Antibody WB Recombinant protein protein 18726-1-AP

WB results of LC3C-specific antibody with Recombinant protein LC3A, LC3B and LC3C, by Dr. Christos Zois.

LC3C-Specific Antibody IF Chloroquine treated HepG2 cells 18726-1-AP

Immunofluorescent analysis of Chloroquine treated HepG2 cells using 18726-1-AP(LC3C-Specific antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Species specificity:
human
Positive WB detected in:
Recombinant protein
Positive IF detected in:
Chloroquine treated HepG2 cells
Recommended dilution:
WB : 1:500-1:1000
IF : 1:20-1:200
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Peptide
Full name:
microtubule-associated protein 1 light chain 3 gamma
Calculated molecular weight:
17 kDa
Observed molecular weight:
GenBank accession number:
NM_001004343
Gene ID (NCBI):
440738
Gene symbol
MAP1LC3C
Synonyms
LC3C, MAP1A/MAP1B LC3 C, MAP1A/MAP1B light chain 3 C, MAP1LC3C

Background

LC3C, also named as MAP1LC3C, belongs to the MAP1 LC3 family. It is the human homolog of yeast Atg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3C is produced by the proteolytic cleavage after the conserved C-terminal Gly residue. The antibody is specific to the prepeptide of LC3C.


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