Cat no : mta
ChromoTek’s MK2-Trap Agarose are affinity beads for IP of MK2-fusion proteins. It comprises a MK2 Nanobody/ VHH conjugated to agarose beads.
|Specificity/Target||MK2 (MAP kinase-activated protein kinase 2, MAPKAP-K2)|
Species-Reactivity: Tested on human, mouse, hamster
Posttranslational modifications: MK2-Trap recognizes unphosphorylated MK2 and Phospho-MK2 (Thr222). Specificity on Phospho-MK2 (Thr334) was not tested.
|Coupled VHH||Recombinant, monoclonal anti-MK2 single domain antibody (sdAb) fragment|
|Beads||~ 90 µm (cross-linked 4 % agarose beads)|
|Elution buffer||SDS sample buffer|
0.2 M glycine pH 2.5
|Storage Buffer||20% EtOH|
|Storage Condition||Upon receipt store at +4°C. Do not freeze!|
Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.
Proc Natl Acad Sci U S A
MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate.