MKL1/MRTF-A Recombinant antibody, PBS Only

MKL1/MRTF-A {ptg:Brand} Recombinant Antibody for WB, Indirect ELISA
Cat No. 84903-1-PBS
Clone No.242021B4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

MKL1, MRTFA, MKL/myocardin-like protein 1, MAL, KIAA1438

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

84903-1-PBS targets MKL1/MRTF-A in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen MKL1/MRTF-A fusion protein Ag15308 Predict reactive species
Full Name megakaryoblastic leukemia (translocation) 1
Calculated Molecular Weight 931 aa, 99 kDa
Observed Molecular Weight145-160 kDa
GenBank Accession NumberBC115039
Gene Symbol MKL1
Gene ID (NCBI) 57591
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ969V6
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Megakaryocytic leukemia 1 (MKL1), also known as myocardin-related transcription factor A (MRTF-A), is a transcriptional regulator involved in a wide range of pathophysiological processes in the cardiovascular system. MKL1 was initially identified as a co-factor for serum response factor (SRF) to regulate the transcription of contractile genes. Forced expression of MKL1 in non-muscle cells leads to robust up-regulation of contractile genes (PMID: 36587486, PMID: 37199168, PMID: 39222836). MKL1 is ubiquitously expressed and has been detected in lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, muscle, heart, and brain. The molecular weight of MKL1 observed is consistent with what has been described in the literature (PMID: 34944031).

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