MSX1 Polyclonal antibody

MSX1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 17678-1-AP

Synonyms

Homeobox protein Hox 7, Homeobox protein MSX 1, HOX7, HYD1, msh homeobox 1, Msh homeobox 1 like protein, MSX1

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Validation Data Gallery

• 

  WB analysis of mouse skeletal muscle using 17678-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17678-1-AP (MSX1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rat skeletal muscle using 17678-1-AP

  rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17678-1-AP (MSX1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse skeletal muscle using 17678-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17678-1-AP (MSX1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse skeletal muscle tissue, rat skeletal muscle tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

The immunogen of 17678-1-AP is MSX1 Fusion Protein expressed in E. coli.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: MSX1 fusion protein Ag11700
• Full Name: msh homeobox 1
• Calculated Molecular Weight: 303 aa, 32 kDa
• Observed Molecular Weight: 32 kDa
• GenBank Accession Number: BC021285
• Gene Symbol: MSX1
• Gene ID (NCBI): 4487
• RRID: AB_2878426
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

MSX1, also known as, Homeobox protein Hox-7 or Msh homeobox 1-like protein, is a 303 maino acid protein, which plays an important role during embryogenesis. Msx1 was the first mammalian member of the Msx subfamily of homeobox genes that was described,and it was isolated from a cDNA library prepared from mouse 8.5-day embryos. Expression of Msx1 has been described during embryogenesis of limb buds, genital ridges, visceral arches, craniofacial structures, central nervous system, and the developing pituitary gland. Msx1 expression in adult mouse uterus and mammary gland has also been reported recently. (PMID: 9369446). MSX1 displays homology to the Drosophilamuscle segment homeobox (msh) gene, which is important in development. MSX1 encodes important genes that regulate numerous morphogenic events, such as tooth formation, bone development, development of the central nervous system, and the development and proliferation of various cell types (PMID: 18379900) .

Publications

Species	Application	Title
human,mouse	WB	Oncogene; LINC01021 maintains tumorigenicity by enhancing N6-methyladenosine reader IMP2 dependent stabilization of MSX1 and JARID2: implication in colorectal cancer.; Authors - Huizhe Wu