MYO18A Monoclonal antibody, PBS Only

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  WB analysis using 68868-1-Ig (same clone as 68868-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68868-1-Ig (MYO18A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68868-1-PBS in a different storage buffer formulation.

MYO18A Monoclonal Antibody for WB, ELISA

Cat No. 68868-1-PBS

Clone No.1A2B12

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

Synonyms

myosinXVIIIA, myosin XVIIIA, Molecule associated with JAK3 N-terminus, KIAA0216, CD245

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Product Information

68868-1-PBS targets MYO18A in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag6185

  Product name: Recombinant human MYO18A protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1601-2002 aa of BC039612

  Sequence: TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA

• Full Name: myosin XVIIIA
• Calculated Molecular Weight: 233 kDa
• GenBank Accession Number: BC039612
• Gene Symbol: MYO18A
• Gene ID (NCBI): 399687
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q92614
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

MYO18A is an unconventional myosin that may play a role in the stabilization and organization of the actin cytoskeleton. Recently MYO18A has been identified as the receptor of SP and is responsible for clearance of SP-A-opsonized bacteria in in vivo infection. Two different isoforms of mouse Myo18A have been identified: Myo18A-alpha and Myo18A-beta as 230- and 190-kDa proteins, respectively. Myo18a-alpha colocalizes with the ER-Golgi complex and with membrane ruffles and filopodia, while Myo18a-beta localizes diffusely to the cytoplasm.