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Recombinant Mouse CD79B protein (rFc Tag)

Species

Mouse

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg2113

Validation Data Gallery

  • Purity of Recombinant Mouse CD79B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse CD79B was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

Product Information

Purity >90 %, SDS-PAGE
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Mouse CD79B protein Val26-Asp158 (Accession# P15530) with a rabbit IgG Fc tag at the C-terminus.
GeneID 15985
Accession P15530
PredictedSize 41.4 kDa
SDS-PAGE 47-60 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily. CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency. CD79b mutation could be a key biomarker for DLBCL disease progression.

References:

1. C J van Noesel, et al. (1991). J Immunol. Jun 1;146(11):3881-8.
2. C J Van Noesel, et al. (1992). J Exp Med. Jun 1;175(6):1511-9.
3. J Hombach, et al. (1990). Nature. Feb 22;343(6260):760-2.
4. C Bonnerot, et al. (1995). Immunity. Sep;3(3):335-47.
5. Peng-Peng Xu, et al. (2022). Clin Lymphoma Myeloma Leuk. Dec;22(12):e1051-e1058.e1.