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Tested Applications
| Positive WB detected in | Jurkat cells, Neuro-2a cells, mouse brain tissue, rat brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
| IHC | See 2 publications below |
| ELISA | See 1 publications below |
Product Information
20246-1-AP targets Neogenin-Specific in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | neogenin homolog 1 (chicken) |
| Calculated Molecular Weight | 160 kDa |
| Observed Molecular Weight | 180 kDa |
| GenBank Accession Number | NM_002499 |
| Gene Symbol | Neogenin |
| Gene ID (NCBI) | 4756 |
| RRID | AB_10695051 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q92859 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
NEO1, also named as IGDCC2 and NGN, belongs to the immunoglobulin superfamily and DCC family. NEO1 may be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. NEO1 may also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues. This antibody is specific to NEO1.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Neogenin-Specific antibody 20246-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Reproduction Deep RNA sequencing analysis of syncytialization-related genes during BeWo cell fusion. | ||
Hum Vaccin Immunother Hamster neogenin, a host-cell protein contained in a respiratory syncytial virus candidate vaccine, induces antibody responses in rabbits but not in clinical trial participants. | ||
Front Mol Neurosci Upregulation of Netrin-1 in the hippocampus mediates the formation of visceral hypersensitivity induced by maternal separation | ||
Cell Death Discov Neogenin suppresses tumor progression and metastasis via inhibiting Merlin/YAP signaling |
