NEURL4 Polyclonal antibody, PBS Only

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• NEURL4 Polyclonal antibody, PBS Only (55345-1-PBS)

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  WB analysis using 55345-1-AP (same clone as 55345-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55345-1-AP (NEURL4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55345-1-PBS in a different storage buffer formulation.

NEURL4 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55345-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

Neuralized-like protein 4, Neuralized like protein 4, KIAA1787

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Product Information

55345-1-PBS targets NEURL4 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: neuralized homolog 4 (Drosophila)
• Calculated Molecular Weight: 167 kDa
• Observed Molecular Weight: 166 kDa
• GenBank Accession Number: NM_032442
• Gene Symbol: NEURL4
• Gene ID (NCBI): 84461
• RRID: AB_2721158
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q96JN8
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NEURL4, also known as KIAA1787, has 6 highly conserved neuralized homology repeats (NHRs), which are thought to mediate protein-protein interactions. NEURL4 localizes to the daughter centriole and prevents formation of ectopic microtubule-organizing centers. NEURL4 promotes CCP110 ubiquitination and proteasome-dependent degradation, maintaining normal centrosomal homeostasis and preventing the formation of abnormal microtubule tissue centers (MTOCs) by countering CP110 accumulation(PMID: 22441691, 22261722).