NFATC3 Monoclonal antibody

NFATC3 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1C1H8

Cat no : 66924-1-Ig

Synonyms

NF AT4, NF ATc3, NFAT4, NFATC3, NFATX



Tested Applications

Positive WB detected inJurkat cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

66924-1-Ig targets NFATC3 in WB,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NFATC3 fusion protein Ag27306
Full Name nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Calculated molecular weight 116 kDa
Observed molecular weight 160 kDa
GenBank accession numberBC001050
Gene symbol NFATC3
Gene ID (NCBI) 4775
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

NFAT (nuclear factors of activated T cells) proteins are a family of transcription factors originally identified as mediators of activation of cytokine genes in response to antigenic stimulation of T cells. NFAT proteins also play varied roles in cells outside of the immune system [PMID:11877454]. NFATc3 has specifically been implicated in vasculature development, regulation of smooth muscle contractile phenotype, and modulation of vascular smooth muscle contractility [PMID:11439183,17148444]. The calculated molecular weight of NFATC3 is 115 kDa, but the post-modified protein is about 130-170 kDa (PMID: 15728531, PMID: 15857835)

Protocols

Product Specific Protocols
WB protocol for NFATC3 antibody 66924-1-IgDownload protocol
Standard Protocols
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