Product Information
87818-1-PBS targets NKG2E in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg4703 Product name: recombinant human NKG2E protein Source: mammalian cells-derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 94-240 aa of NM_002261.3 Sequence: IPFLEQNNSSPNARTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLQACASKNSSSLLCIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS Predict reactive species |
| Full Name | killer cell lectin-like receptor subfamily C, member 3 |
| Calculated Molecular Weight | 37 kDa |
| Observed Molecular Weight | 45-60 kDa |
| GenBank Accession Number | NM_002261.3 |
| Gene Symbol | KLRC3 |
| Gene ID (NCBI) | 3823 |
| RRID | AB_3745768 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q07444-1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
NKG2E, also known as killer cell lectin-like receptor subfamily C member 3 (KLRC3), is a transmembrane protein primarily expressed on the surface of natural killer (NK) cells and some cytotoxic T-cells. As a member of the NKG2 family, it functions as a receptor for the recognition of non-classical MHC class I molecule HLA-E, playing a role in immune surveillance. Structurally, NKG2E is a type II membrane protein containing a C-type lectin domain in its extracellular region. The immunogenic sequence of NKG2E shares 88% homology with that of NKG2A, leading to cross-reactivity.
