Product Information
84278-5-PBS targets NME3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, rat samples.
Tested Reactivity | human, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | NME3 fusion protein Ag7284 Predict reactive species |
Full Name | non-metastatic cells 3, protein expressed in |
Calculated Molecular Weight | 19 kDa |
Observed Molecular Weight | 18 kDa |
GenBank Accession Number | BC000250 |
Gene Symbol | NME3 |
Gene ID (NCBI) | 4832 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q13232 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3), also named as NM23-H3; DR-NM23, is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. The depletion of NME3 will cause dysfunction in mitochondrial dynamics. NME3 has been found to facilitate DNA-repair mechanisms binds to several NPHPs, including NEK8, CEP164, and ankyrin repeat and sterile α motif domain-containing 6 (ANKS6)