Product Information
85608-3-PBS targets NPL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | NPL fusion protein Ag10137 Predict reactive species |
Full Name | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
Calculated Molecular Weight | 27 kDa, 35 kDa |
Observed Molecular Weight | 35 kDa |
GenBank Accession Number | BC058003 |
Gene Symbol | NPL |
Gene ID (NCBI) | 80896 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9BXD5 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
The N-acetylneuraminate lyase(NPL) from human (hNAL) which consists of 320 amino acids, has a molecular mass of 35.2 kDa and it catalyses the reversible aldol reaction of sialic acid, and has been extensively used in the synthesis of sialic acids and its analogues(PMID:19057931). The enzyme is widely distributed and are present in numerous pro- and eukaryotic cells, in which they are localized only in the cytosol(PMID:12453637). It belongs to the DHDPS family and has 5 isoforms produced by alternative splicing.