Product Information
87535-4-PBS targets NPLOC4 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Ag2219 Product name: Recombinant human NPLOC4 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 261-608 aa of BC025930 Sequence: DIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNMCRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQLPGLHEYGAVGGSTHTATAAMWACQHCTFMNQPGTGHCEMCSLPRT Predict reactive species |
| Full Name | nuclear protein localization 4 homolog (S. cerevisiae) |
| Calculated Molecular Weight | 608 aa, 68 kDa |
| Observed Molecular Weight | 68-75 kDa |
| GenBank Accession Number | BC025930 |
| Gene Symbol | NPLOC4 |
| Gene ID (NCBI) | 55666 |
| RRID | AB_3745606 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q8TAT6 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
NPLOC4 (NPL4 ubiquitin recognition factor) is an essential protein involved in numerous cellular processes, especially those related to the endoplasmic reticulum (ER) . It acts as a co-factor in the p97/VCP complex, which is vital for protein quality control and degradation via the ubiquitin-proteasome system. NPLOC4 plays a significant role in ER-associated degradation (ERAD), maintaining cellular homeostasis.
