NPRL2,TUSC4 Recombinant monoclonal antibody, PBS Only

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• NPRL2,TUSC4 Recombinant monoclonal antibody, PBS Only (88066-1-PBS)

• 

  WB analysis using 88066-1-RR (same clone as 88066-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88066-1-RR (NPRL2,TUSC4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88066-1-PBS in a different storage buffer formulation.

NPRL2,TUSC4 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 88066-1-PBS

Clone No.251619D5

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

TUSC4, G21 protein, GATOR1 complex protein NPRL2, Gene 21 protein, Nitrogen permease regulator 2-like protein

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Product Information

88066-1-PBS targets NPRL2,TUSC4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag38610

  Product name: Recombinant human NPRL2,TUSC4 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-270 aa of BC002791

  Sequence: GCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSMEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGH

• Full Name: tumor suppressor candidate 4
• Calculated Molecular Weight: 44 kDa
• Observed Molecular Weight: 44 kDa
• GenBank Accession Number: BC002791
• Gene Symbol: TUSC4
• Gene ID (NCBI): 10641
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8WTW4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NPRL2 (NPR2 Like, GATOR1 Complex Subunit) is a Protein Coding gene associated with Epilepsy, Familial Focal. As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. Homologous to yeast nitrogen permease (candidate tumor suppressor) (NM_006545, BC021984) gene encodes a protein of molecular mass of 50 kDa. Data by using overlapping and nested homozygous deletions methods indicate that this protein might be a tumor suppressor involved in the development of lung cancers.