HRP-conjugated NR2E3 Monoclonal antibody

NR2E3 Monoclonal Antibody for WB

Host / Isotype

Mouse / IgG1

Reactivity

Pig

Applications

WB

Conjugate

HRP

CloneNo.

1G1D9

Cat no : HRP-66494

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37



Tested Applications

Positive WB detected inpig retina tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

HRP-66494 targets NR2E3 in WB applications and shows reactivity with Pig samples.

Tested Reactivity Pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NR2E3 fusion protein Ag5831
Full Name nuclear receptor subfamily 2, group E, member 3
Calculated Molecular Weight 45 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC041421
Gene Symbol NR2E3
Gene ID (NCBI) 10002
RRIDAB_2883842
Conjugate HRP
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]

Protocols

Product Specific Protocols
WB protocol for HRP NR2E3 antibody HRP-66494Download protocol
Standard Protocols
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