HRP-conjugated NR2E3 Monoclonal antibody

NR2E3 Monoclonal Antibody for WB

Host / Isotype

Mouse / IgG1

Reactivity

Pig

Applications

WB

Conjugate

HRP

CloneNo.

1G1D9

Cat no : HRP-66494

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37

---

Validation Data Gallery

• 

  WB analysis of pig retina using HRP-66494

  pig retina tissue were subjected to SDS PAGE followed by western blot with HRP-66494 (NR2E3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

---

Tested Applications

• Positive WB detected in: pig retina tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

HRP-66494 targets NR2E3 in WB applications and shows reactivity with Pig samples.

• Tested Reactivity: Pig
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: NR2E3 fusion protein Ag5831
• Full Name: nuclear receptor subfamily 2, group E, member 3
• Calculated Molecular Weight: 45 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: BC041421
• Gene Symbol: NR2E3
• Gene ID (NCBI): 10002
• RRID: AB_2883842
• Conjugate: HRP
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]