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NRAMP1 Polyclonal antibody, PBS Only

NRAMP1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 32308-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

SLC11A1, NRAMP 1

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

32308-1-PBS targets NRAMP1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

Peptide

Predict reactive species
Full Name solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Calculated Molecular Weight 432 aa, 48 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC071165
Gene Symbol SLC11A1
Gene ID (NCBI) 6556
RRIDAB_3742575
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity Purification
UNIPROT IDP49279
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SLC11A1 also known as NRAMP1, belongs to the SLC11 family of solute carriers, which mediate the transport of divalent metals. NRAMP1 is a divalent metal importer specifically expressed in the membranes of late endosomes/lysosomes of professional phagocytes. It plays a crucial role in the defense against intracellular pathogens by depleting essential metal ions from endocytosed microbes, thereby preventing their proliferation(PMID: 24832660, PMID: 39824808).

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