NRG1, isoform SMDF Monoclonal antibody

NRG1, isoform SMDF Monoclonal Antibody for WB, IF, ELISA

Host / Isotype

Mouse / IgG1


Human, pig, mouse, rat, rabbit







Cat no : 66492-1-Ig


ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF

Tested Applications

Positive WB detected inrat brain tissue, HepG2 cells, pig cerebellum tissue, rat cerebellum tissue, mouse cerebellum tissue, mouse brain tissue, rabbit brain tissue
Positive IF detected inMCF-7 cells

Recommended dilution

Western Blot (WB)WB : 1:5000-1:50000
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66492-1-Ig targets NRG1, isoform SMDF in WB, IF, IHC, ELISA applications and shows reactivity with Human, pig, mouse, rat, rabbit samples.

Tested Reactivity Human, pig, mouse, rat, rabbit
Cited Reactivitymouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NRG1, isoform SMDF fusion protein Ag0803
Full Name neuregulin 1
Calculated Molecular Weight 70 kDa
Observed Molecular Weight 70 kDa
GenBank Accession NumberBC007675
Gene Symbol NRG1
Gene ID (NCBI) 3084
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The antibody is specific to NRG1 isoform SMDF.


Product Specific Protocols
WB protocol for NRG1, isoform SMDF antibody 66492-1-IgDownload protocol
IF protocol for NRG1, isoform SMDF antibody 66492-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Prog Neuropsychopharmacol Biol Psychiatry

The Notch1/Hes1 pathway regulates Neuregulin 1/ErbB4 and participates in microglial activation in rats with VPA-induced autism

Authors - Yanan Deng

J Cell Mol Med

PMID: 32073745

Authors - Jianxia Wen

Int J Mol Sci

Dysregulation of ErbB4 Signaling Pathway in the Dorsal Hippocampus after Neonatal Hypoxia-Ischemia and Late Deficits in PV+ Interneurons, Synaptic Plasticity and Working Memory

Authors - Harisa Spahic