NRG1 Monoclonal antibody

NRG1 Monoclonal Antibody for IF, WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, mouse, rat, rabbit

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

CloneNo.

2C6D12

Cat no : 66492-1-Ig

Synonyms

ARIA, GGF, GGF2, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, neuregulin 1, NRG1, Pro NRG1, SMDF



Tested Applications

Positive WB detected inpig brain tissue, HepG2 cells, mouse cerebellum tissue, pig cerebellum tissue, rat brain tissue, rat cerebellum tissue, mouse brain tissue, rabbit brain tissue
Positive IF detected inMCF-7 cells
Planning an IF experiment? We recommend our CoraLite®488 and CoraLite®594 conjugated versions of this antibody.

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:12000
Immunofluorescence (IF)IF : 1:200-1:800
Sample-dependent, check data in validation data gallery

Published Applications

IHCSee 1 publications below

Product Information

66492-1-Ig targets NRG1 in WB, IHC, IF, ELISA applications and shows reactivity with Human, pig, mouse, rat, rabbit samples.

Tested Reactivity Human, pig, mouse, rat, rabbit
Cited Reactivityrat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen NRG1 fusion protein Ag0803
Full Name neuregulin 1
Calculated molecular weight 32 kDa
Observed molecular weight 70 kDa
GenBank accession numberBC007675
Gene symbol NRG1
Gene ID (NCBI) 3084
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain.

Protocols

Product Specific Protocols
WB protocol for NRG1 antibody 66492-1-IgDownload protocol
IF protocol for NRG1 antibody 66492-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratIHC

J Cell Mol Med

PMID: 32073745

Authors - Jianxia Wen