Product Information
19923-1-PBS targets NSG1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag13888 Product name: Recombinant human D4S234E protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-185 aa of BC001745 Sequence: MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA Predict reactive species |
| Full Name | DNA segment on chromosome 4 (unique) 234 expressed sequence |
| Calculated Molecular Weight | 185 aa, 21 kDa |
| Observed Molecular Weight | 16-21 kDa |
| GenBank Accession Number | BC001745 |
| Gene Symbol | D4S234E |
| Gene ID (NCBI) | 27065 |
| RRID | AB_3741973 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P42857 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
NSG1, also known as Neuron-Enriched Endosomal Protein of 21 kDa (NEEP21) , is a protein encoded by the NSG1 gene located on human chromosome 4p16.3 . The Neuron-Specific Gene (NSG) family includes NSG1, NSG2, and NSG3. As their name indicates they are expressed almost exclusively in neurons, and localize to multiple subcellular organelles including the Golgi apparatus, early and late endosomes, and the plasma membrane. As a highly enriched endosomal protein within neuronal cells, NSG1 has been discovered to facilitate the process of epithelial-mesenchymal transition (EMT) in esophageal squamous cell carcinoma (ESCC).(PMID: 37872157,PMID: 41415429)
