OPN4 Recombinant monoclonal antibody

• Home
• Products
• Primary Antibodies
• Recombinant Antibodies
• OPN4 Recombinant monoclonal antibody (87397-1-RR)

• 

  WB analysis of mouse eye using 87397-1-RR

  mouse eye tissue were subjected to SDS PAGE followed by western blot with 87397-1-RR (OPN4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

OPN4 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 87397-1-RR

Clone No.251643A9

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

Melanopsin, MOP, opsin 4, Opsin-4

---

Tested Applications

• Positive WB detected in: mouse eye tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

87397-1-RR targets OPN4 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: opsin 4
• Calculated Molecular Weight: 478 aa, 53 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: BC113558
• Gene Symbol: OPN4
• Gene ID (NCBI): 94233
• RRID: AB_3745515
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9UHM6
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

OPN4, an opsin that was first isolated from the skin of Xenopus laevis in 1998, belongs not to the vertebrate-type opsin family but rather to the invertebrate-type opsins, which are part of the seven-transmembrane G protein-coupled receptor (GPCR) family (PMID:31989708). In humans, OPN4 is expressed in the retinal ganglion cells in addition to part of the brain (PMID:10632589). Moreover, Opn4 functions as a photoreceptor by detecting brightness levels and discriminating visual signals (PMID:22633808). Opn4 also facilitates visual circuits to acquire optimal settings and light adaptation by measuring irradiance levels (PMID:25517373).