OPRL1 Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• OPRL1 Polyclonal antibody, PBS Only (12970-1-PBS)

• 

  WB analysis of HeLa using 12970-1-AP (same clone as 12970-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 12970-1-AP (OPRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• 

  WB analysis of SH-SY5Y using 12970-1-AP (same clone as 12970-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 12970-1-AP (OPRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• 

  IP experiment of SH-SY5Y using 12970-1-AP (same clone as 12970-1-PBS)

  IP result of anti-OPRL1 (IP:12970-1-AP, 4ug; Detection:12970-1-AP 1:500) with SH-SY5Y cells lysate 2000ug. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 12970-1-AP (OPRL1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 12970-1-AP (OPRL1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12970-1-AP (OPRL1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

OPRL1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Cat No. 12970-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Synonyms

---

Product Information

12970-1-PBS targets OPRL1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag4079

  Product name: Recombinant human OPRL1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 71-370 aa of BC038433

  Sequence: LVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALACKTSETVPRPA

• Full Name: opiate receptor-like 1
• Calculated Molecular Weight: 370 aa, 41 kDa
• Observed Molecular Weight: 45 kDa
• GenBank Accession Number: BC038433
• Gene Symbol: OPRL1
• Gene ID (NCBI): 4987
• RRID: AB_10638603
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P41146
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

The OPRL1 (opioid related nociceptin receptor 1) is the G-protein coupled receptor activated by the endogenou NC (neuropeptide nociceptin) (PMID:7566152). OPRL1 is widely expressed in the central nervous system, including the hippocampal dentate gyrus, cortical areas, striatum, thalamus, and hypothalamus (PMID:19501074). OPRL1 has been found to play an essential role in cognition, and to modulate inflammation and immune responses (PMID:30152845).