ORAI2 Polyclonal antibody
ORAI2 Polyclonal Antibody for FC, IF, IHC, WB,ELISA
Host / Isotype
Rabbit / IgG
human, mouse and More (1)
WB, IP, IHC, IF, FC, ELISA
Cat no : 20592-1-AP
|Positive WB detected in||MCF-7 cells, mouse heart tissue|
|Positive IHC detected in||human kidney tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HEK-293 cells|
|Positive FC detected in||HEK-293 cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Immunofluorescence (IF)||IF : 1:10-1:100|
|Sample-dependent, check data in validation data gallery|
The immunogen of 20592-1-AP is ORAI2 Fusion Protein expressed in E. coli.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||ORAI2 fusion protein Ag14540|
|Full Name||ORAI calcium release-activated calcium modulator 2|
|Calculated molecular weight||254 aa, 29 kDa|
|Observed molecular weight||36 kDa|
|GenBank accession number||BC069270|
|Gene ID (NCBI)||80228|
|Purification Method||Antigen Affinity purified|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
ORAI2, also named as C7orf19, CBCIP2, TMEM142B and PP1729, is a Ca2+ release-activated Ca2+-like (CRAC-like) channel subunit. The MW of ORAI2 is about 36 kDa for glycosylation (PMID: 19675303).
|Product Specific Protocols|
|WB protocol for ORAI2 antibody 20592-1-AP||Download protocol|
|IHC protocol for ORAI2 antibody 20592-1-AP||Download protocol|
|IF protocol for ORAI2 antibody 20592-1-AP||Download protocol|
|FC protocol for ORAI2 antibody 20592-1-AP||Download protocol|
|Click here to view our Standard Protocols|
J Am Heart Assoc
Cardiac-Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice.
Front Mol Biosci
X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca2+ Influx in Rat Brain Microvascular Endothelial Cells.
BMJ Open Diabetes Res Care
Orai-vascular endothelial-cadherin signaling complex regulates high-glucose exposure-induced increased permeability of mouse aortic endothelial cells.
Exp Ther Med
Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation.
Bisbenzylisoquinoline alkaloids from Plumula Nelumbinis inhibit vascular smooth muscle cells migration and proliferation by regulating the ORAI2/Akt pathway
Allergy Asthma Immunol Res
Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca2+ Entry Pathway
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Marcel (Verified Customer) (03-20-2023)