Product Information
85408-5-PBS targets PARN in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | PARN fusion protein Ag4774 Predict reactive species |
Full Name | poly(A)-specific ribonuclease (deadenylation nuclease) |
Calculated Molecular Weight | 639 aa, 73 kDa |
Observed Molecular Weight | 74 kDa |
GenBank Accession Number | BC050029 |
Gene Symbol | PARN |
Gene ID (NCBI) | 5073 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O95453 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Poly(A)-specific ribonuclease (PARN) is a deadenylase enzyme that is present in mammalian cells. As a deadenylase, PARN interacts with the cap and the poly(A) tail of mRNA to control the length of the poly(A) tail and regulate gene expression. Therefore, it plays a role in mRNA degradation in the nucleus and cytoplasm.