PCDHB10 Polyclonal antibody, PBS Only

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• PCDHB10 Polyclonal antibody, PBS Only (14785-1-PBS)

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  IHC staining of human pancreas cancer using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas cancer using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 14785-1-AP (same clone as 14785-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14785-1-PBS in a different storage buffer formulation.

PCDHB10 Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 14785-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Synonyms

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Product Information

14785-1-PBS targets PCDHB10 in IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag6427

  Product name: Recombinant human PCDHB10 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 400-696 aa of BC031837

  Sequence: FYILITEGALDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHLLLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVAL

• Full Name: protocadherin beta 10
• Calculated Molecular Weight: 88 kDa
• GenBank Accession Number: BC031837
• Gene Symbol: PCDHB10
• Gene ID (NCBI): 56126
• RRID: AB_3669193
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UN67
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHB10 belongs to the β-protocadherin (PCDHB) cluster. PCDHB cluster acts as a DNA methylation marker of aggressiveness in neuroblastoma (PMID: 26103900).