PDGF-D Polyclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• PDGF-D Polyclonal antibody, PBS Only (14075-1-PBS)

• 

  IHC staining of human colon cancer using 14075-1-AP (same clone as 14075-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 14075-1-AP (PDGF-D antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14075-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 14075-1-AP (same clone as 14075-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 14075-1-AP (PDGF-D antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14075-1-PBS in a different storage buffer formulation.

• 

  IF Staining of rat brain using 14075-1-AP (same clone as 14075-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed rat brain tissue using PDGFD antibody (14075-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14075-1-PBS in a different storage buffer formulation.

• 

  IF Staining of rat brain using 14075-1-AP (same clone as 14075-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed rat brain tissue using PDGFD antibody (14075-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 14075-1-PBS in a different storage buffer formulation.

• 

  IF Staining of A549 using 14075-1-AP (same clone as 14075-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A549 cells using PDGFD antibody (14075-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 14075-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

PDGF-D Polyclonal Antibody for IHC, IF/ICC, IF-P, Indirect ELISA

Cat No. 14075-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

IHC, IF/ICC, IF-P, Indirect ELISA

Synonyms

PDGFD, Iris-expressed growth factor, PDGF D, PDGFD receptor binding form, Platelet-derived growth factor D

---

Product Information

14075-1-PBS targets PDGF-D in IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag5154

  Product name: Recombinant human PDGFD protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-364 aa of BC030645

  Sequence: MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAASETNWESVTSSISGVSYNSPSVTDPTLIADALDKKIAEFDTVEDLLKYFNPESWQEDLENMYLDTPRYRGRSYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR

• Full Name: platelet derived growth factor D
• Calculated Molecular Weight: 43 kDa
• GenBank Accession Number: BC030645
• Gene Symbol: PDGFD
• Gene ID (NCBI): 80310
• RRID: AB_2162208
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9GZP0
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Platelet-derived growth factor-D (PDGF-D) is the newest member of the PDGF family. It is secreted as a latent dimer that must undergo extracellular proteolytic removal of its N-terminal CUB domain before the growth-factor domain can activate the β-PDGFR. Once activated, PDGF-D drives proliferation, migration and survival of mesenchymal cells and promotes angiogenesis, wound healing and tissue remodeling. Clinically, PDGF-D is up-regulated in several cancers and in fibrotic diseases of the heart, kidney and lung, making it a potential therapeutic target.