FcZero-rAb® Biotin Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody

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• FcZero-rAb® Biotin Anti-Human PDGFR alpha/CD140a Rabbit Recombinant Antibody (Biotin-FcA98141)

• Zero Fc receptor binding
• Site-specific conjugation
• One universal isotype

PDGFR alpha/CD140a FcZero-rAb^® Recombinant Antibody for FC

Cat No. Biotin-FcA98141

Clone No.241658H4

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

PDGFRA, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140A

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  FC experiment of MG-63 using Biotin-FcA98141

  1x10^6 MG-63 cells (left) or A-172 cells (right) were surface stained with 0.25 ug Biotin Anti-Human PDGFR alpha/CD140a Rabbit RecAb (Biotin-FcA98141, Clone: 241658H4) (red) or FcZero-rAb® Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9) (blue), and Streptavidin-PE Conjugate (PE-PF00030). Cells were not fixed.

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Tested Applications

• Positive FC detected in: MG-63 cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

Biotin-FcA98141 targets PDGFR alpha/CD140a in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant Protein

• Full Name: platelet-derived growth factor receptor, alpha polypeptide
• Calculated Molecular Weight: 123 kDa
• GenBank Accession Number: BC015186
• Gene Symbol: PDGFR alpha
• Gene ID (NCBI): 5156
• Conjugate: Biotin
• Excitation/Emission Maxima Wavelengths: -
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P16234
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Platelet-derived growth factor receptor alpha (PDGFR alpha, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival, and chemotaxis. Mutations in the PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.