PDI Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 11245-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
COLO 320 cells, HEK-293 cells, HepG2 cells, human brain tissue, human thyroid gland tissue, mouse heart tissue, mouse thymus tissue, rat brain tissue, rat heart tissue, rat thymus tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human prostate cancer tissue, human lung cancer tissue, human prostate cancer tissue

Positive IF detected in:
HEK-293 cells, HepG2 cells

Positive FC detected in:
HEK-293T cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
prolyl 4-hydroxylase, beta polypeptide

Calculated molecular weight:
57 kDa

Observed molecular weight:
57 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
P4HB

Synonyms
DSI, ERBA2L, GIT, P4HB, P4Hbeta, p55, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB, Protein disulfide isomerase
Background

PDIA1(Protein disulfide-isomerase) is also named as ERBA2L, PDI, P4HB, PO4DB. It is a multifunctional protein that catalyzes the formation, breakage and rearrangement of disulfide bonds. In some cell types, it seems to be secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources.It can exsit as homodimer and monomers and homotetramers may also occur(PMID:12095988).


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