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PKC eta Polyclonal antibody, PBS Only

PKC eta Polyclonal Antibody for WB, Indirect ELISA

Cat No. 26916-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

PRKCH, PKC L, PKCL, PRKCL, Protein kinase C eta type

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

26916-1-PBS targets PKC eta in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag25365

Product name: Recombinant human PRKCH protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 634-683 aa of BC037268

Sequence: RIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQP

Predict reactive species
Full Name protein kinase C, eta
Observed Molecular Weight75-90 kDa
GenBank Accession NumberBC037268
Gene Symbol PRKCH
Gene ID (NCBI) 5583
RRIDAB_3742204
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP24723
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

PRKCH (gene ID: 5583) encodes protein kinase C eta (PKCη), a calcium‑independent, phospholipid‑dependent serine/threonine kinase of the novel PKC subfamily. It regulates cell proliferation, differentiation, and apoptosis, with prominent roles in keratinocyte differentiation, early B‑cell development, and epithelial barrier integrity. Genetic variants in PRKCH are linked to cerebral infarction and Alzheimer's disease, while PKCη exhibits context‑dependent functions in cancer-promoting progression and chemoresistance in some tumors (e.g., glioblastoma) but acting as a tumor suppressor in others (e.g., hepatocellular carcinoma).

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