Product Information
33028-1-PBS targets PLEKHN1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38741 Product name: Recombinant human PLEKHN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 200-350 aa of BC101386 Sequence: SAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGS Predict reactive species |
| Full Name | pleckstrin homology domain containing, family N member 1 |
| Calculated Molecular Weight | 663 aa, 72 kDa |
| Observed Molecular Weight | 66-71 kDa |
| GenBank Accession Number | BC101386 |
| Gene Symbol | PLEKHN1 |
| Gene ID (NCBI) | 84069 |
| RRID | AB_3742825 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q494U1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
PLEKHN1 (Pleckstrin Homology Domain Containing N1) is a protein-coding gene located on chromosome 1. It plays a crucial role in various cellular processes, including apoptosis and mRNA stability regulation. PLEKHN1 has been identified as a pro-apoptotic protein that enhances Bax-Bak hetero-oligomerization via interaction with Bid in colon cancer cells. (PMID: 29531808)
