POLG2 Recombinant antibody, PBS Only

• 

  WB analysis using 85852-4-RR (same clone as 85852-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85852-4-RR (POLG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85852-4-PBS in a different storage buffer formulation.

• 

  WB analysis using 85852-4-RR (same clone as 85852-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85852-4-RR (POLG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85852-4-PBS in a different storage buffer formulation.

POLG2 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85852-4-PBS

Clone No.250198G10

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

DNA polymerase subunit gamma-2, MTPOLB, p55, PEOA4, POLGB

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Product Information

85852-4-PBS targets POLG2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: POLG2 fusion protein Ag1424
• Full Name: polymerase (DNA directed), gamma 2, accessory subunit
• Calculated Molecular Weight: 55 kDa
• Observed Molecular Weight: 52-55 kDa
• GenBank Accession Number: BC009194
• Gene Symbol: POLG2
• Gene ID (NCBI): 11232
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9UHN1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

by POLG) and an accessory subunit (encoded by POLG2). POLG2(DNA polymerase subunit gamma-2, mitochondrial) can stimulate the polymerase and exonuclease activities (PMID: 37085601). Defects in POLG2 are the cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 4 (PEOA4) (PMID: 16685652).Western blot result suggested that the POLG2 expressed in cell lines with a single band of 52-55kd.