Product Information
12461-1-PBS targets PPP1R1A in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3128 Product name: Recombinant human PPP1R1A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-171 aa of BC022470 Sequence: MEQDNSPQKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSV Predict reactive species |
| Full Name | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| Calculated Molecular Weight | 171 aa, 19 kDa |
| Observed Molecular Weight | 15-18 kDa |
| GenBank Accession Number | BC022470 |
| Gene Symbol | PPP1R1A |
| Gene ID (NCBI) | 5502 |
| RRID | AB_3741828 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13522 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
PPP1R1A, also known as protein phosphatase 1 regulatory subunit 1A, is a gene that plays a crucial role in regulating the activity of protein phosphatase 1 (PP1). As an inhibitor, PPP1R1A binds to PP1, preventing the dephosphorylation of PP1 to other proteins. This gene influences a broad range of cellular functions by maintaining the phosphorylation of specific proteins and is directly involved in glycogen metabolism, cardiac contractility, and cell proliferation. PPP1R1A is considered a key factor in regulating cellular signaling and physiological homeostasis.
