PR Polyclonal antibody

PR Polyclonal Antibody for IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 25871-1-AP


NR3C3, PGR, PR, progesterone receptor

Tested Applications

Positive IHC detected inhuman breast cancer tissue, human ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inT-47D cells

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 25871-1-AP is PR Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PR fusion protein Ag22986
Full Name progesterone receptor
Calculated molecular weight 933 aa, 99 kDa
Observed molecular weight80 kDa, 110-115 kDa
GenBank accession numberNM_000926
Gene symbol PGR
Gene ID (NCBI) 5241
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.


Product Specific Protocols
WB protocol for PR antibody 25871-1-APDownload protocol
IHC protocol for PR antibody 25871-1-APDownload protocol
IF protocol for PR antibody 25871-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



BMC Complement Med Ther

Bushen Huoxue recipe attenuates early pregnancy loss via activating endometrial COX2-PGE2 angiogenic signaling in mice.

Authors - Yufan Song

Front Vet Sci

Hybrid Broussonetia papyrifera Fermented Feed Can Play a Role Through Flavonoid Extracts to Increase Milk Production and Milk Fatty Acid Synthesis in Dairy Goats.

Authors - Mengjie Zhao

Reprod Sci

The Possibility of Analyzing Endometrial Receptivity Using Cells from Embryo Transfer Catheters.

Authors - Kaori Goto

Biosci Rep

Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.

Authors - Jiahong Tan

Int Immunopharmacol

BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.

Authors - Lan Lin

Breast Cancer Res Treat

Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.

Authors - Christopher Khayeka-Wandabwa