PRMT7 Polyclonal antibody, PBS Only

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• PRMT7 Polyclonal antibody, PBS Only (21688-1-PBS)

• 

  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 21688-1-AP (same clone as 21688-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21688-1-AP (PRMT7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HeLa using 21688-1-AP (same clone as 21688-1-PBS)

  IP result of anti-PRMT7 (IP:21688-1-AP, 4ug; Detection:21688-1-AP 1:1000) with HeLa cells lysate 1400 ug. This data was developed using the same antibody clone with 21688-1-PBS in a different storage buffer formulation.

PRMT7 Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 21688-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IP, Indirect ELISA

Synonyms

Protein arginine N-methyltransferase 7, PRMT 7, Histone-arginine N-methyltransferase PRMT7, EC:2.1.1.321, [Myelin basic protein]-arginine N-methyltransferase PRMT7

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Product Information

21688-1-PBS targets PRMT7 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag16269

  Product name: Recombinant human PRMT7 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 353-693 aa of BC000146

  Sequence: PEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSVCLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWYVRTAVDQHLGPGAMVMPQAASLHAVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVPLQPLCAEGTVELRRPGQSHAAVLWMEYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDPRALLGGPRTVSYAVEFHPDTGDIIMEFRHADTPD

• Full Name: protein arginine methyltransferase 7
• Calculated Molecular Weight: 78 kDa
• Observed Molecular Weight: 73-78 kDa
• GenBank Accession Number: BC000146
• Gene Symbol: PRMT7
• Gene ID (NCBI): 54496
• RRID: AB_3742051
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9NVM4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.