PRMT7 Monoclonal antibody

PRMT7 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, rat and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

3C5H6

Cat no : 67669-1-Ig

Synonyms

FLJ10640, KIAA1933, PRMT7



Tested Applications

Positive WB detected inHeLa cells, HSC-T6 cells, HepG2 cells, Jurkat cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 2 publications below

Product Information

67669-1-Ig targets PRMT7 in WB, ELISA applications and shows reactivity with Human, rat samples.

Tested Reactivity Human, rat
Cited Reactivityhuman
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen PRMT7 fusion protein Ag30434
Full Name protein arginine methyltransferase 7
Calculated Molecular Weight 78 kDa
Observed Molecular Weight78 kDa
GenBank Accession NumberBC000146
Gene Symbol PRMT7
Gene ID (NCBI) 54496
RRIDAB_2882865
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.

Protocols

Product Specific Protocols
WB protocol for PRMT7 antibody 67669-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Gastroenterology

Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms

Authors - Ming Zhang
humanWB

EMBO J

MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

Authors - Yan Sun