|Positive WB detected in||HeLa cells, HSC-T6 cells, HepG2 cells, Jurkat cells|
|Western Blot (WB)||WB : 1:1000-1:6000|
|Sample-dependent, check data in validation data gallery|
67669-1-Ig targets PRMT7 in WB, ELISA applications and shows reactivity with Human, rat samples.
|Tested Reactivity||Human, rat|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||PRMT7 fusion protein Ag30434|
|Full Name||protein arginine methyltransferase 7|
|Calculated molecular weight||78 kDa|
|Observed molecular weight||78 kDa|
|GenBank accession number||BC000146|
|Gene ID (NCBI)||54496|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.