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PTOV1 Polyclonal antibody, PBS Only

PTOV1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 16575-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

ACID2, Activator interaction domain-containing protein 2, PP642, prostate tumor overexpressed 1, Prostate tumor-overexpressed gene 1 protein

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

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Freight/Packing: -

Quantity

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Product Information

16575-1-PBS targets PTOV1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag9859

Product name: Recombinant human PTOV1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 57-416 aa of BC042921

Sequence: MEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGMGG

Predict reactive species
Full Name prostate tumor overexpressed 1
Calculated Molecular Weight 416 aa, 47 kDa
Observed Molecular Weight58 kDa
GenBank Accession NumberBC042921
Gene Symbol PTOV1
Gene ID (NCBI) 53635
RRIDAB_3741887
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ86YD1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

PTOV1 is a dual-domain adaptor and transcriptional co-regulator that promotes cell proliferation and oncogenic signaling through interactions with E2F1, RSK, and Mediator components. Shuttling between cytoplasm and nucleus, it integrates growth factor and differentiation pathways to balance proliferation and differentiation. Overexpressed in multiple cancers-most prominently prostate carcinoma-PTOV1 is linked to tumor progression, therapy resistance, and poor prognosis, positioning it as a potential biomarker and therapeutic target in epithelial malignancies. (PMID: 15713644)

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