Product Information
16315-1-PBS targets PXK in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag9362 Product name: Recombinant human PXK protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-352 aa of BC014479 Sequence: MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKLLPSCLHPYIYRVTFATANESSALLIRMFNEKGTLKDLIYKAKPKDPFLKKYCNPKKIQGLELQQIKTYGRQILEVLKFLHDKGFPYGHLHASNVMLDGDTCRLLDLENSLLGLPSFYRSYFSQFRKINTLESVDVHCFGHLLYEMTYGRPPD Predict reactive species |
| Full Name | PX domain containing serine/threonine kinase |
| Calculated Molecular Weight | 450aa,52 kDa; 578aa,65 kDa |
| Observed Molecular Weight | 55 kDa |
| GenBank Accession Number | BC014479 |
| Gene Symbol | PXK |
| Gene ID (NCBI) | 54899 |
| RRID | AB_3669237 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q7Z7A4 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
PXK is part of the sorting nexin (SNX) family of proteins, which are important for receptor internalization, organelle trafficking including endosomal trafficking, and other membrane-centric sorting functions. This is accomplished primarily through the PX-domain mediated binding of PI3P . PXK was first identified and cloned by two independent groups in 2005. Initial studies established that PXK is detectable in most tissues with a primarily cytoplasmic distribution. (PMID: 25620976)
