Phospho-ATG4B (Ser383) Recombinant antibody, PBS Only

Phospho-ATG4B (Ser383) Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85703-1-PBS
Clone No.242927A2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ATG4B, APG4B, AUTL1, AUT-like 1 cysteine endopeptidase, Autophagin-1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

85703-1-PBS targets Phospho-ATG4B (Ser383) in applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Peptide Predict reactive species
Full Name ATG4 autophagy related 4 homolog B (S. cerevisiae)
Calculated Molecular Weight 44 kDa
Observed Molecular Weight44-48 kDa
GenBank Accession NumberBC000719
Gene Symbol ATG4B
Gene ID (NCBI) 23192
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9Y4P1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

ATG4B stimulates autophagy by promoting autophagosome formation through reversible modification of ATG8. In humans, microtubule-associated protein 1 light chain, LC3B, is the best-characterized ATG8 isoform, and ATG4B, but not three other ATG4 isoforms, displays a highly selective preference toward LC3B. MST4 phosphorylates ATG4B at serine residue 383, which stimulates ATG4B activity and increases autophagic flux. (PMID: 29232556, PMID: 36056541)

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