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Plakophilin 1 Recombinant antibody

Plakophilin 1 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 85217-4-RR
Clone No.242834G8

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

PKP1, 242834G8, B6P, Plakophilin-1

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration:  100 μL, 1000 μg/ml
20 μL, 1000 μg/ml
100 μL, 1000 μg/ml

$449/ 100 μL

In stock in Rosemont, IL. Order within 86 hours and 6 mins to receive by Tuesday, July 1

Freight/Packing: $40.00

Quantity

Tested Applications

Positive WB detected inmouse skin tissue, HEK-293 cells, A431 cells, PC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

85217-4-RR targets Plakophilin 1 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Plakophilin 1 fusion protein Ag18153 Predict reactive species
Full Name plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
Calculated Molecular Weight 747 aa, 83 kDa
Observed Molecular Weight70-75 kDa
GenBank Accession NumberBC114571
Gene Symbol PKP1
Gene ID (NCBI) 5317
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13835
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Plakophilin 1, also known as PKP1, B6P, is a member of the arm-repeat protein family. PKP1 contains arm-repeat (armadillo) domains, localizes to nuclei and cell desmosomes, and participates in linking cadherins to intermediate filaments in the cytoskeleton (PMID: 10747098). PKP1 contributes to epidermal morphogenesis and facilitates the formation of intermediate filaments. Mutations in PKP1 have been associated with the ectodermal dysplasia/skin fragility syndrome (PubMed:9326952, 10852826).

Protocols

Product Specific Protocols
WB protocol for Plakophilin 1 antibody 85217-4-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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