RAB11A/B Recombinant monoclonal antibody, PBS Only

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• RAB11A/B Recombinant monoclonal antibody, PBS Only (87237-1-PBS)

RAB11A/B Uni-rAb^® Recombinant Antibody for WB, IP, Indirect ELISA

Cat No. 87237-1-PBS

Clone No.252492E7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Synonyms

Rab 11, RAB11, RAB11A, EC:3.6.5.2, Rab-11

• 

  WB analysis using 87237-1-RR (same clone as 87237-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 87237-1-RR (RAB11A antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87237-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of A431 using 87237-1-RR (same clone as 87237-1-PBS)

  WB result of RAB11A/B antibody (87237-1-RR; 1:12000; incubated at room temperature for 1.5 hours) with sh-Control and sh-RAB11A/B transfected A431 cells. This data was developed using the same antibody clone with 87237-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  IP experiment of mouse spleen using 87237-1-RR (same clone as 87237-1-PBS)

  IP result of anti-RAB11A/B (IP:87237-1-RR, 4ug; Detection:87237-1-RR 1:3000) with mouse spleen tissue lysate 2000 ug. This data was developed using the same antibody clone with 87237-1-PBS in a different storage buffer formulation.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Product Information

87237-1-PBS targets RAB11A/B in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag8742

  Product name: Recombinant human RAB11A protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-216 aa of BC013348

  Sequence: MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI

• Full Name: RAB11A, member RAS oncogene family
• Calculated Molecular Weight: 216 aa, 24 kDa
• Observed Molecular Weight: 24 kDa
• GenBank Accession Number: BC013348
• Gene Symbol: RAB11A
• Gene ID (NCBI): 8766
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P62491
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

RAB11 has two isoform genes RAB11A(YL8) and RAB11B(YPT3), and belongs to the small GTPase superfamily and Rab family. It regulates endocytic recycling. RAB11 may exert its functions by interacting with multiple effector proteins in different complexes. It acts as a major regulator of membrane delivery during cytokinesis. RAB11 regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. This antibody can recognize both RAB11A(24 kDa) and RAB11B(24 kDa).