Product Information
20154-1-PBS targets RAD9B in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag14009 Product name: Recombinant human RAD9B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 83-426 aa of BC068031 Sequence: CKLGMKSILPIFRCLNSLERNIEKCRIFTRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFTSSQEEVTLAVTPLNFCLKSSNEESMDLSNAVHSEMFVGSDEFDFFQIGMDTEITFCFKELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCLSQKRKRSDLIEKKAGKNVTGQALECISKKAAPRRLYPKETLTNISALENCGSPAMKRVDGDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMNNVCCRKEFNGSDAKYFCII Predict reactive species |
| Full Name | RAD9 homolog B (S. pombe) |
| Calculated Molecular Weight | 426 aa, 48 kDa |
| Observed Molecular Weight | 48 kDa |
| GenBank Accession Number | BC068031 |
| Gene Symbol | RAD9B |
| Gene ID (NCBI) | 144715 |
| RRID | AB_3741978 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6WBX8 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
RAD9B is a key member of the DNA damage response and cell cycle checkpoint family. Homologous to RAD9A, it typically functions as a subunit of the 9-1-1 complex (RAD9B-RAD1-HUS1), which is loaded onto chromatin in response to DNA damage or replication stress. This complex activates the ATM/ATR kinase pathway to mediate cell cycle arrest, DNA repair, or apoptosis.
