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RGS9 Polyclonal antibody, PBS Only

RGS9 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 17970-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

PERRS, Regulator of G-protein signaling 9, RGS9L

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

17970-1-PBS targets RGS9 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag11976

Product name: Recombinant human RGS9 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 273-622 aa of BC022504

Sequence: SGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVPTGSGTCLMDSEDAGTGESGDRATEKEVICPWESL

Predict reactive species
Full Name regulator of G-protein signaling 9
Calculated Molecular Weight 622 aa, 71 kDa
Observed Molecular Weight 50-58 kDa, 70-75 kDa
GenBank Accession NumberBC022504
Gene Symbol RGS9
Gene ID (NCBI) 8787
RRIDAB_2178508
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO75916
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).

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