Product Information
31223-1-PBS targets RIN2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag35011 Product name: Recombinant human RIN2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-150 aa of NM_018993 Sequence: MLDSFSQESTLPFREARKRTSFQPVQVWRNFTASQTTESPACSGASLGEMTAWTMGARGLDKRGSFFKLIDTIASEIGELKQEMVRTDVNLENGLEPAETHSMVRHKDGGYSEEEDVKTCARDSGYDSLSNRLSILDRLLHTHPIWLQLS Predict reactive species |
| Full Name | Ras and Rab interactor 2 |
| Calculated Molecular Weight | 100 kDa |
| Observed Molecular Weight | 100-120 kDa |
| GenBank Accession Number | NM_018993 |
| Gene Symbol | RIN2 |
| Gene ID (NCBI) | 54453 |
| RRID | AB_3742411 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WYP3 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
RIN2 (Ras and Rab interactor 2), also known as RASSF4. RIN2 is mainly located in Golgi apparatus and participates in the process of material transport and secretion in cells. It is also distributed in cytoplasmic matrix, which may be related to signal transduction in cells. It is highly expressed in the brain, and also in the cerebellum, spinal cord and other nervous system tissues. RIN2 belongs to the family of Ras and Rab exchange factors and has a unique VPS9 domain. It can be used as a nucleotide exchange factor to activate the downstream small GTP enzymes Rab5 and R-Ras, thus starting intracellular signal transduction and regulating cytoskeleton recombination, synapse secretion and cell adhesion. The molecular weight of RIN2 is 100 kDa.
