SAMD9L Recombinant antibody

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  WB analysis using 84109-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84109-1-RR (SAMD9L antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84109-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84109-1-RR against Human SAMD9L were performed. The affinity constant is 1.14 nM.

SAMD9L Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 84109-1-RR

Clone No.241250A2

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

Sterile alpha motif domain-containing protein 9-like, SAM domain-containing protein 9-like, KIAA2005, DRIF2, C7orf6

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Tested Applications

• Positive WB detected in: mouse brain tissue, NIH/3T3 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84109-1-RR targets SAMD9L in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SAMD9L fusion protein Ag18541
• Full Name: sterile alpha motif domain containing 9-like
• Calculated Molecular Weight: 1584 aa, 185 kDa
• Observed Molecular Weight: 160-180 kDa
• GenBank Accession Number: BC127118
• Gene Symbol: SAMD9L
• Gene ID (NCBI): 219285
• RRID: AB_3671676
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q8IVG5
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Sterile alpha motif domain-containing protein 9-like(SAMD9L), also named C7orf6, DRIF2, KIAA2005, and UEF, is a cytoplasmic protein that acts as a tumor suppressor but also plays a key role in cell proliferation and the innate immune response to viral infection. SAMD9L protein is an endosome fusion facilitator that causes myeloid malignancies in mice similar to human diseases with monosomy 7. The SAMD9L protein also appears to play an important role in the brain, particularly the part of the brain that coordinates movement (the cerebellum). SAMD9L has two isoforms with MW 185 kDa and 47 kDa.