SC4MOL Recombinant antibody, PBS Only

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  WB analysis using 84742-1-RR (same clone as 84742-1-PBS)

  mouse adipose tissue were subjected to SDS PAGE followed by western blot with 84742-1-RR (SC4MOL antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84742-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84742-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84742-1-RR against Human SC4MOL were performed. The affinity constant is 12.3 nM.

SC4MOL Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 84742-1-PBS

Clone No.241988B11

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

ERG25, DESP4, 241988B11

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Product Information

84742-1-PBS targets SC4MOL in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: SC4MOL fusion protein Ag34758
• Full Name: sterol-C4-methyl oxidase-like
• Observed Molecular Weight: 36 kDa
• GenBank Accession Number: BC107879
• Gene Symbol: SC4MOL
• Gene ID (NCBI): 6307
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q15800
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SC4MOL(sterol C4-methyl oxidase-like), an intermediate enzyme in the cholesterol biosynthetic pathway, was included in the library based on its representation in a high confidence GEO transcriptional profiling dataset as a transcript that rapidly undergoes significant expression change in response to stimulation or inhibition of EGFR. Among the validated hits that increased cell killing by common EGFR antagonists, SC4MOL was consistently one of the most effective modulators. (PMID: 23125191)